Synthesis of a highly functionalized core of verrillin.

نویسندگان

  • Alec Saitman
  • Emmanuel A Theodorakis
چکیده

An efficient stereoselective synthesis of furanoverrillin (5), a highly functionalized core of verrillin (1), is reported. The synthetic strategy is based on constructing bicyclic lactone 17 prior to the 10-membered ring macrocyclization. The effect of the C4 methyl group on the furan reactivity is also discussed.

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عنوان ژورنال:
  • Organic letters

دوره 15 10  شماره 

صفحات  -

تاریخ انتشار 2013